Studies on analogues of L-cysteine and L-cystine. II. The effect of selenium cystine on Murphy lymphosarcoma tumor cells in the rat.

Studies on analogues of L-cysteine and L-cystine. III. The effect of selenium cystine on leukemia.

-CYSTEINE and related (omnpoumsds appear to have au importatit uole in the rnetabolismn of leukocytes. 6 A decrease its the availability of L-cyst-eine or L_cystimie* may therefore have important effects ots beukocyt-es. The Icukocytes of acute leukemia amid chromuic myeloid beukemia exhibit a niore rapid turmiover of radioactive L-cystiise thams do normnal leukocytes.7’ 8 Leukensic leukocytes ...

Translocation of Calcium in the Bean Plant.

11. FINKLE, B. J. and APPLEMAN, D. The effect of magnesium concentration on growth of Chlorella. Plant Physiol. 28: 664-673. 1953. 12. FOWDEN, L. The effect of age on the bulk protein composition of Chlorella vulgaris. Biochem. Jour. 52: 310314. 1952. 13. GROSS, D. and TARVER, H. Studies on ethionine. IV. The incorporation of ethionine into the proteins of Tetrahymena. Jour. Biol. Chem. 217: 16...

Studies on analogues of L-cysteine and L-cystine. I. Some structural requirements for inhibiting the incorporation of radioactive L-cystine by leukemic leukocytes.

Molecular mechanisms of cystine transport.

The transport of L-cystine into cells of the mammalian brain is an essential step in the supply of cysteine for synthesis of the antioxidant glutathione. Uptake of L-cystine in rat brain synaptosomes occurs by three mechanisms that are distinguishable on the basis of their ionic dependence, kinetics of transport and specificity of inhibitors. Almost 90% of L-cystine transport is by a low-affini...

The synthesis of S-benzylthiopyruvic acid and its conversion to N-acetyl-S-benzyl-L-cysteine in the rat; unavailability of thiopyruvic acid to rats for growth purposes.

Some time ago we demonstrated the acetylation of S-benzyl-L-cysteine in the dog, rabbit, rat, and man (l-3). Administration of S-benzyl-ncysteine to rats (4, 5) or man (3) was followed by the excretion of some N-acetyl-S-benzyl-L-cysteine, thus indicating a partial inversion of the D derivative of cysteine to the optical antipode. Ample experimental evidence is available to show that oxidative ...